Surface modification of biomaterials : methods, analysis and applications

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The surface modification of biomaterials plays a significant role in determining the outcome of biological-material interactions. With the appropriate modification a material's surface can be tailored to improve biocompatibility, adhesion and cell interactions. Consequently surface modification is vital in the development and design of new biomaterials and medical devices. Surface modification of biomaterials reviews both established surface modifications and those still in the early stages of research and discusses how they can be used to optimise biological interactions and enhance clinical performance. Part one begins with chapters looking at various types and techniques of surface modification including plasma polymerisation, covalent binding of poly (ethylene glycol) (PEG), heparinisation, peptide functionalisation and calcium phosphate deposition before going on to examine metal surface oxidation and biomaterial surface topography to control cellular response with particular reference to technologies, cell behaviour and biomedical applications. Part two studies the analytical techniques and applications of surface modification with chapters on analysing biomaterial surface chemistry, surface structure, morphology and topography before moving onto discuss modifying biomaterial surfaces to optimise interactions with blood, control infection, optimise interactions with soft tissues, repair and regenerate nerve cells, control stem cell growth and differentiation and to optimise interactions with bone.- … full description

Bibliographic Details

Other Authors

R. L. Williams
ScienceDirect (online služba)

Document Type

Books

Physical Description

1 online zdroj (xvi, 415 stran) : ilustrace

Published

Oxford ; Cambridge ; Philadelphia ; New Delhi : Woodhead Publishing, 2011

Edition

First edition

Series

Woodhead Publishing series in biomaterials

Subjects

materiálové inženýrství > sr

biomateriály > bi

biomedicínské materiály > zd

povrch > ob

příručky

elektronické knihy

more… less…

Bibliography

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ISBN

978-0-85709-076-8