The antimicrobial susceptibility and virulence factors of Bacillus anthracis strains isolated in Croatia

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Bacillus anthracis can infect both livestock and humans. The importance of the treatment of the disease in humans has been underscored by the bioterrorism events of 2001 in the United States. The presence of PA and B/C genes (pX01 and pX02 plasmids) as well as susceptibility to several antimicrobial substances was determined in 11 strains of Bacillus anthracis isolated during two recent epizooties of anthrax which occurred in Croatia in 2002 among sheep and in 2006/2007 in cattle. The pX01 plasmid was observed in all of the examined strains, including vaccinal Sterne strains. However, the pX02 plasmid was detected in only eight out of eleven examined field strains of Bacillus anthracis while in vaccinal strains it was not detected at. Determination of MIC’s revealed susceptibility to amoxicillin, amoxicillin with clavulanic acid, ciprofloxacin, gentamicin and tetracycline. All strains were resistant to sulfamethoxazole with trimethoprim and cefotaxime. … full description

Bibliographic Details

Other Authors

Boris Habrun, I. Racic, G. Kompes, S. Spicić, M. Benić, Z. Mihaljevic, Željko Cvetnić

Document Type

Articles

Physical Description

2 il., 1 mapa

Published in

Veterinární medicína. -- ISSN 0375-8427. -- Roč. 56, č. 1 (2011), s. 22-27

Subjects

CROATIA

BACILLUS ANTHRACIS

MICROBIOLOGICAL ANALYSIS

MICROBIAL PROPERTIES

PATHOGENICITY

DRUG RESISTANCE

ANTIMICROBIALS

ANTIBIOTICS

GENES

PLASMIDS

SURVEYS

EPIDEMICS

SHEEP

CATTLE

Bacillus anthracis

mikrobiologická analýza

mikrobiální vlastnosti

patogenita

rezistence k lékům

antimikrobiální látky

antibiotika

geny

plazmidy

průzkumy

epidemie

ovce

skot

Chorvatsko

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Item Description

2 tabulky

Bibliography

Literatura na s. 27