Comparison of estradiol and progesteron serum levels in ferrets suffering from hyperoestrogenism and ovarian neoplasia

Get it

The aim of this study was to determine whether serum levels of 17beta-estradiol and progesterone are significant diagnostic tools for the confirmation of specific reproductive diseases associated with hyperestrogenism. Thirty-one adult ferrets (Mustela putorrius furo) were divided into five groups. The levels of serum 17beta-estradiol differed significantly when comparing females with ovarian tumors (817.80 ± 433.90 pmol/l) to intact (83.50 ± 32.53 pmol/l) and spayed, healthy females (73.17 ± 0.41 pmol/l) as well as to females with prolonged estrus (274.75 ± 192.40 pmol/l). Concentrations of serum progesterone differed significantly when comparing females with ovarian tumours (2.10 ± 1.85 ng/ml) to intact (0.40 ± 0.40 ng/ml) and spayed, healthy females (0.30 ± 0.12 ng/ml). Our study has made it clear that a determination of serum concentrations of 17-beta estradiol and progesterone is not sufficient for distinguishing between prolonged estrus and the presence of ovarian tumours. Therefore, it is advisable to employ other clinical procedures, such as ones allowing organ visualization. Increased concentrations of 17beta-estradiol in ferrets persisted for two weeks after hCG administration. This is particularly important in clinical practice, as negative effects of estrogens on bone marrow could persist for more than 14 days. Therefore, ferrets should be clinically monitored for a longer period of time. … full description

Bibliographic Details

Other Authors

Karel Hauptman , Vladimír Jekl, 1977- , G. M. Dorrestein, Mirko Vyskočil, Zdeněk Knotek, 1956-

Document Type

Articles

Physical Description

1 il.

Published in

Veterinární medicína. -- ISSN 0375-8427. -- Roč. 54, č. 11 (2009), s. 532-536

Subjects

PET ANIMALS

FERRETS

FEMALES

FEMALE GENITAL SYSTEM

OESTROUS CYCLE

HORMONAL CONTROL

DISORDERS

OESTROGENS

OVARIES

NEOPLASMS

CASTRATION

DIFFERENTIAL DIAGNOSIS

BLOOD SERUM

SEX HORMONES

PROGESTERONE

domácí zvířata

fretky

samice

samičí pohlavní systém

pohlavní cyklus

hormonální regulace

poruchy

estrogeny

vaječníky

neoplazmy

kastrace

diferenční diagnóza

krevní sérum

pohlavní hormony

progesteron

hyperestrogenismus

prodloužený estrus

17 beta estradiol

Item Description

1 tabulka

Bibliography

Literatura na s. 535-536